A Micropigmentação da área de sobrancelha: Caracterização de tintas e estudo clínico randomizado para avaliar a longevidade dos pigmentos na pele
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Abstract
With technological advances in aesthetics, new products for micropigmentation are emerging, increasing the need for scientific proof of the quality and action of products in the body. The present study aimed to evaluate the inks containing organic (P1) and inorganic (P2) pigments used in micropigmentation of the eyebrow area regarding the permanence time of the injected ink and physicochemical characterization. The parallel clinical study was applied according to the CONSORT 2010 guidelines. Where the intervention phase was composed of the inclusion of 36 research subjects selected according to the inclusion and exclusion criteria; random allocation into two groups, G1 and G2, who received interventions with P1 and P2, respectively; follow-up occurred at time zero, after 2 and 6 months; and from the exogenous pigmentation monitored using digital photography and GIMP® software, it was possible to convert the qualitative analysis into quantitative and treat the data statistically. The inks were characterized physically for pigment morphology using Scanning Electron Microscope and chemically for elemental analysis using Energy Dispersive Spectroscopy. There was no statistical difference between the amounts of a dark color (in percentage) in the images obtained (p < 0.05), consequently, the permanence time of P1 and P2 in the micropigmentations of the eyebrow area analyzed at 6 months was similar (0. 07 ± 0.03% and 0.06 ± 0.04% for P1 and P2, respectively). The ink containing P1 had larger particle sizes, smaller size distribution, and a more regular shape than the ink containing P2. However, the pigment particles' type, size, and shape did not impact a significant difference (p<0.05) in fixation and longevity between P1 and P2 pigments in micropigmentation of the eyebrow area. Although further investigations are necessary to evaluate this phenomenon.
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